Global & Disaster Medicine

A fractional dose (1/5) of the 17DD yellow fever vaccine: Effective?

 

NEJM

“….In 2016, the response to a yellow fever outbreak in Angola and the Democratic Republic of Congo led to a global shortage of yellow fever vaccine. As a result, a fractional dose of the 17DD yellow fever vaccine (containing one fifth [0.1 ml] of the standard dose) was offered to 7.6 million children 2 years of age or older and nonpregnant adults in a preemptive campaign in Kinshasa. …………

A fractional dose of the 17DD yellow fever vaccine was effective at inducing seroconversion in most of the participants ….”

 


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