Global & Disaster Medicine

Since January 2018, 10 travel-related cases of yellow fever, including four deaths, have been reported in international travelers returning from Brazil.

MMWR

Characteristics of five travelers to Brazil with yellow fever reported by GeoSentinel sites, January–March 2018*Return to your place in the text
Characteristic Patient 1 (man) Patient 2 (woman) Patient 3 (man) Patient 4 (man) Patient 5 (man)
Age (yrs) 46 42 34 44 33
Nationality Dutch French Romanian Swiss German
Reporting site Netherlands France Romania Switzerland United Kingdom
Area (state) of presumed yellow fever acquisition Mairiporã (São Paulo) (Minas Gerais) Ilha Grande (Rio de Janeiro) Ilha Grande (Rio de Janeiro) Ilha Grande (Rio de Janeiro)
Signs/Symptoms Fever, headache, myalgia, nausea, vomiting, diarrhea Fever Fever, rash, myalgia, encephalopathy Fever, petechial rash, arthralgia, vomiting, diarrhea Fever, malaise, nausea, jaundice, hepatomegaly
Clinical/Laboratory findings Hepatitis Hepatitis, thrombocytopenia, neutropenia Renal and hepatic failure Renal and hepatic failure Thrombocytopenia, renal and hepatic failure
Yellow fever diagnostic testing Positive RT-PCR for YFV (urine, whole blood, plasma) Positive RT-PCR (blood); positive IgM (initial diagnosis made in Brazil) Positive PCR (serum, urine); YF IgM positive; IgG titers rising days 4–8 Positive PCR (blood) Positive RT-PCR (serum, urine)
Yellow fever vaccination status No No No No No
Outcome Recovered Recovered Condition improving as of March 15, 2018 Died Died

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