Global & Disaster Medicine

Results from a phase 2 trial of a live-attenuated, measles-vectored chikungunya vaccine (MV-CHIK) showed the vaccine to be safe, well-tolerated, and immunogenic.

Lancet

Immunogenicity, safety, and tolerability of the measles-vectored chikungunya virus vaccine MV-CHIK: a double-blind, randomised, placebo-controlled and active-controlled phase 2 trial

DOI:https://doi.org/10.1016/S0140-6736(18)32488-7

Countries with current or previous local transmission of chikungunya virus, listed in below data table

CDC

Symptoms

  • Most people infected with chikungunya virus will develop some symptoms.
  • Symptoms usually begin 3–7 days after being bitten by an infected mosquito.
  • The most common symptoms are fever and joint pain.
  • Other symptoms may include headache, muscle pain, joint swelling, or rash.
  • Chikungunya disease does not often result in death, but the symptoms can be severe and disabling.
  • Most patients feel better within a week. In some people, the joint pain may persist for months.
  • People at risk for more severe disease include newborns infected around the time of birth, older adults (≥65 years), and people with medical conditions such as high blood pressure, diabetes, or heart disease.
  • Once a person has been infected, he or she is likely to be protected from future infections.

Diagnosis

  • The symptoms of chikungunya are similar to those of dengue and Zika, diseases spread by the same mosquitoes that transmit chikungunya.
  • See your healthcare provider if you develop the symptoms described above and have visited an area where chikungunya is found.
  • If you have recently traveled, tell your healthcare provider when and where you traveled.
  • Your healthcare provider may order blood tests to look for chikungunya or other similar viruses like dengue and Zika.

Treatment

  • There is no vaccine to prevent or medicine to treat chikungunya virus.
  • Treat the symptoms:
    • Get plenty of rest.
    • Drink fluids to prevent dehydration.
    • Take medicine such as acetaminophen (Tylenol®) or paracetamol to reduce fever and pain.
    • Do not take aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS until dengue can be ruled out to reduce the risk of bleeding).
    • If you are taking medicine for another medical condition, talk to your healthcare provider before taking additional medication.
  • If you have chikungunya, prevent mosquito bites for the first week of your illness.
    • During the first week of infection, chikungunya virus can be found in the blood and passed from an infected person to a mosquito through mosquito bites.
    • An infected mosquito can then spread the virus to other people.

More detailed information can be found on CDC’s chikungunya web page for healthcare providers

 


Comments are closed.

Categories

Recent Posts

Archives

Admin