Global & Disaster Medicine

Mass distribution of azithromycin could be a strategy for reducing childhood mortality in parts of sub-Saharan Africa.

NEJM

“…..it remains unclear how azithromycin might be preventing childhood deaths. “Thus far our general sense is that azithromycin may work better in places with the highest childhood mortality, and these places have a very high burden of infectious illnesses, so we think azithromycin very likely is treating a multitude of infections that might ultimately have caused a death,” he [study co-author and University of California-San Francisco ophthalmology professor Jeremy Keenan, MD, MPH] said.

Other theories include a benefit to childhood growth, a change in gut microbiota, or an anti-inflammatory effect…..”


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