Global & Disaster Medicine

Archive for the ‘WHO’ Category

WHO Director-General: Though the spread of Ebola to Uganda is a new development, it doesn’t signal a shift in outbreak dynamics.

WHO

14 June 2019

Thank you, Dr Aavitsland,

Good evening from DRC.

I would like to thank Dr Aavitsland for his leadership of the Emergency Committee, and all the members of the committee, as well as the advisors and those who made presentations.

As you have heard, the Emergency Committee has recommended for a third time, and I have agreed, that the current Ebola outbreak in DRC does not constitute a public health emergency of international concern.

Although the outbreak does not at this time pose a global health threat, I want to emphasise that for the affected families and communities, this outbreak is very much an emergency.

Today I have been in Kinshasa to discuss the current Ebola outbreak with the Prime Minister of DRC, the Minister of Health, opposition leaders, donors and others.

Tomorrow I will travel to Goma and Butembo, to meet with our incredible staff and partners who are on the frontline of this outbreak.

I will also be traveling to Uganda to assess the situation.

Since the outbreak started last August, there have been 2108 cases of Ebola, and 1411 deaths. This is tragic.

Although the spread of Ebola to Uganda is tragic, it is not a surprise. We have said since the beginning of the outbreak that the risk of cross-border spread was very high, and it remains very high.

The fact that it has taken this long is a testament to the incredible work of all partners on both sides of the border.

I particularly want to commend the Government of Uganda for the way it has responded. So far, the investments they have made and the plans they have put in place to prepare for Ebola are paying off.

The spread of Ebola to Uganda is a new development, but the fundamental dynamics of the outbreak haven’t changed.

We have the people, the tools, the knowledge, and the determination to end this outbreak.

We need the sustained political commitment of all parties, so we can safely access and work with communities.

We also need the international community to step up its financial commitment to ending the outbreak.

WHO’s current funding needs for the period from February to July are 98 million U.S. dollars, of which 43.6 million dollars has been received, leaving a gap of 54 million dollars. We call on all our partners to fill this gap as soon as possible.

I will not hesitate to convene it again if needed.

Thank you.

DRC:

Total cases: 2108
– Confirmed cases: 2014
– Probable cases: 94

Deaths: 1411
– Confirmed: 1317
– Probable: 94


Statement on the meeting of the International Health Regulations (2005) Emergency Committee for Ebola virus disease in the Democratic Republic of the Congo

WHO

14 June 2019

The meeting of the Emergency Committee convened by the WHO Director-General under the International Health Regulations (IHR) (2005) regarding Ebola virus disease in the Democratic Republic of the Congo (DRC) took place on Friday, 14 June 2019, from 12:00 to 17:00 Geneva time (CEST).

Context and Discussion

The Committee expressed its deep concern about the ongoing outbreak, which, despite some positive epidemiological trends, especially in the epicentres of Butembo and Katwa, shows that the extension and/or reinfection of disease in other areas like Mabalako, presents, once again, challenges around community acceptance and security. In addition, the response continues to be hampered by a lack of adequate funding and strained human resources.

The cluster of cases in Uganda is not unexpected; the rapid response and initial containment is a testament to the importance of preparedness in neighbouring countries. The Committee commends the communication and collaboration between DRC and Uganda.

At the same time, the exportation of cases into Uganda is a reminder that, as long as this outbreak continues in DRC, there is a risk of spread to neighbouring countries, although the risk of spread to countries outside the region remains low.

The Committee wishes to commend the heroic work of all responders, who continue to work under extremely challenging and stressful conditions.

The Committee extensively debated the impact of a PHEIC declaration on the response, possible unintended consequences, and how these might be managed. Differing views were expressed, as the Committee acknowledged that recent cases in Uganda constitute international spread of disease.

Conclusions and Advice

It was the view of the Committee that the outbreak is a health emergency in DRC and the region but does not meet all the three criteria for a PHEIC under the IHR. While the outbreak is an extraordinary event, with risk of international spread, the ongoing response would not be enhanced by formal Temporary Recommendations under the IHR (2005).

The Committee provided the following public health advice, which it strongly urges countries and responding partners to heed:

  • At-risk countries should improve their preparedness for detecting and managing exported cases, as Uganda has done.
  • Cross-border screening in DRC should continue and its quality improved and sustained.
  • Continue to map population movements and sociological patterns that can predict risk of disease spread.
  • All priority countries should put in place approvals for investigational medicines and vaccines as an immediate priority for preparedness.
  • Optimal vaccine strategies that have maximum impact on curtailing the outbreak, as recommended by WHO’s Strategic Advisory Group of Experts (SAGE), should be implemented rapidly.
    • The Committee is deeply disappointed that WHO and the affected countries have not received the funding and resources needed for this outbreak. The international community must step up funding and support strengthening of preparedness and response in DRC and neighbouring countries.
    • Continue to strengthen community awareness, engagement, and participation. There has been a great deal of progress in community engagement activities. However, in border communities, where mobility is especially likely, community engagement needs to be more sharply targeted to identify the populations most at risk.
    • The implementation by the UN and partners of more coordinated measures to reduce security threats, mitigate security risks, and create an enabling environment for public health operations is welcomed and encouraged by the Committee as an essential platform for accelerating disease-control efforts.
    • The Committee strongly emphasizes its previous advice against the application of any international travel or trade restrictions.
    • The Committee does not consider entry screening at airports or other ports of entry to be necessary.
  • The Committee advised the WHO Director-General to continue to monitor the situation closely and reconvene the Emergency Committee as needed.

    Proceedings of the meeting

    Members and advisors of the Emergency Committee were convened by teleconference.

    Because the Chair, Dr Robert Steffen, was unable to attend the meeting in person, Dr Preben Aavitsland chaired the proceedings.

    The Director-General welcomed the Committee by phone from the Democratic Republic of the Congo.

    Representatives of WHO’s legal department and the department of compliance, risk management, and ethics briefed the Committee members on their roles and responsibilities, as well as the requirements of the IHR and the criteria that define a PHEIC: an extraordinary event that poses a public health risk to other countries through international spread and that requires a coordinated international response. The Committee’s role is to give advice to the Director-General, who makes the final decision on the determination of a PHEIC. The Committee also provides advice or temporary recommendations as appropriate.

    Committee members were reminded of their duty of confidentiality and their responsibility to disclose personal, financial, or professional connections that might be seen to constitute a conflict of interest. Each member was surveyed and no conflicts of interest were identified.

    The Chair then reviewed the agenda for the meeting and introduced the presenters. Presentations were made by representatives of the Ministry of Health of the Democratic Republic of the Congo and of the National Communicable Disease Control Commission of Uganda.

    The situation in the Democratic Republic of the Congo was reviewed, including the current epidemiological situation and response strategies, including changes instituted to improve community engagement. Sustained, serious security incidents, which have resulted in injuries and deaths among responses have seriously impeded the response. There have been four waves of the outbreak since August 2018, but during the last month there has been a reduction in numbers of cases. Active case-finding for missing contacts is ongoing. Factors contributing to the ongoing outbreak include population movement, health-seeking behavior directed to traditional healers, poor infection prevention and control measures in health facilities, security challenges, and lack of involvement by political leaders.

    Representatives of the National Communicable Disease Control Commission in Uganda reviewed recent cases, contacts, and contact tracing. They updated the Committee on their response actions, including notification to WHO and political involvement, and preparedness activities that have been taking place since August 2018. A national coordination task force has been activated and a rapid response team deployed. Clinical management is available in an Ebola Treatment Unit in Bwera. Screening is taking place at official points of entry. Ring vaccination will begin on 15 June.

    A representative of the WHO Regional Office for Africa presented the status of regional preparedness activities, particularly in Burundi, Rwanda, South Sudan, and Uganda. Ongoing challenges were noted, especially at district/subnational levels, as well as inadequate crossborder collaboration and a lack of funding to sustain preparedness activities.

    A representative of the International Organization for Migration updated the Committee on prevention, detection, and control measures at points of entry, for cross-border preparedness.

    The UN Ebola Emergency Response Coordinator gave an update on the security situation and efforts to create a dynamic, nimble enabling environment to support outbreak response. There have been frequent disruptions to the response, which has had implications for increased numbers of cases. UN-wide support is needed to strengthen the public health response and coordinate international assistance. Access and community acceptance are increasing, with decreases in cases in some areas. Increases in attacks in some areas are being addressed.

    The WHO Secretariat gave an update on the current situation and provided details on the response to the current Ebola outbreak and preparedness activities in neighbouring countries. The risk assessment for DRC remains very high at national and regional levels but low at global level. Risk in Uganda remains moderate at the national level and low and regional and global levels. However, the high risks of the Uganda event have been mitigated by rapid communication and coordination among authorities across jurisdictions; detection at points of entry and subsequent response activities; and operational preparedness and readiness in Uganda. A high level of cooperation and transparency between DRC and Uganda was noted with appreciation.

    There has been an overall decline in case incidence in the last 5 weeks, but substantial rates of transmission continue, especially in a few hotspots. IPC measures, safe burials, and population mobility were reviewed, along with details of contact tracing. Operational scale-up was reviewed and a serious need for funding, both for the response and for preparedness, was underscored. Less than one-third of the resources needed are available; presently there is a funding shortfall of USD $54 million against $98 million needed for the response through July 2019.

    Based on the above advice, the reports made by the affected States Parties, and the currently available information, the Director-General accepted the Committee’s assessment that the Ebola outbreak in the Democratic Republic of the Congo does not constitute a Public Health Emergency of International Concern. In light of the advice of the Emergency Committee, WHO advises against the application of any travel or trade restrictions. The Director-General thanked the Committee Members and Advisors for their advice.


WHO: All about polio

WHO

Key facts

  • Polio (poliomyelitis) mainly affects children under 5 years of age.
  • 1 in 200 infections leads to irreversible paralysis. Among those paralysed, 5% to 10% die when their breathing muscles become immobilized.
  • Cases due to wild poliovirus have decreased by over 99% since 1988, from an estimated 350 000 cases then, to 33 (1) reported cases in 2018.
  • As long as a single child remains infected, children in all countries are at risk of contracting polio. Failure to eradicate polio from these last remaining strongholds could result in as many as 200 000 new cases every year, within 10 years, all over the world.
  • In most countries, the global effort has expanded capacities to tackle other infectious diseases by building effective surveillance and immunization systems.

Symptoms

Polio is a highly infectious disease caused by a virus. It invades the nervous system, and can cause total paralysis in a matter of hours. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (for example, contaminated water or food) and multiplies in the intestine. Initial symptoms are fever, fatigue, headache, vomiting, stiffness of the neck and pain in the limbs. 1 in 200 infections leads to irreversible paralysis (usually in the legs). Among those paralysed, 5% to 10% die when their breathing muscles become immobilized.

People most at risk

Polio mainly affects children under 5 years of age.

Prevention

There is no cure for polio, it can only be prevented. Polio vaccine, given multiple times, can protect a child for life.

Global caseload

Wild poliovirus cases have decreased by over 99% since 1988, from an estimated 350 000 cases in more than 125 endemic countries then, to 33 (1) reported cases in 2018.

Of the 3 strains of wild poliovirus (type 1, type 2, and type 3), wild poliovirus type 2 was eradicated in 1999 and no case of wild poliovirus type 3 has been found since the last reported case in Nigeria in November 2012.

WHO Response

Launch of the Global Polio Eradication Initiative

In 1988, the Forty-first World Health Assembly adopted a resolution for the worldwide eradication of polio. It marked the launch of the Global Polio Eradication Initiative (GPEI), spearheaded by national governments, WHO, Rotary International, the US Centers for Disease Control and Prevention (CDC), UNICEF, and supported by key partners including the Bill & Melinda Gates Foundation. This followed the certification of the eradication of smallpox in 1980, progress during the 1980s towards elimination of the poliovirus in the Americas, and Rotary International’s commitment to raise funds to protect all children from the disease.

Progress

Overall, since the GPEI was launched, the number of cases has fallen by over 99%.

In 1994, the WHO Region of the Americas was certified polio-free, followed by the WHO Western Pacific Region in 2000 and the WHO European Region in June 2002. On 27 March 2014, the WHO South-East Asia Region was certified polio-free, meaning that transmission of wild poliovirus has been interrupted in this bloc of 11 countries stretching from Indonesia to India. This achievement marks a significant leap forward in global eradication, with 80% of the world’s population now living in certified polio-free regions.

More than 16 million people are able to walk today, who would otherwise have been paralysed. An estimated 1.5 million childhood deaths have been prevented, through the systematic administration of vitamin A during polio immunization activities.

Opportunity and risks: an emergency approach

The strategies for polio eradication work when they are fully implemented. This is clearly demonstrated by India’s success in stopping polio in January 2011, in arguably the most technically-challenging place, and polio-free certification of the entire South-East Asia Region of WHO occurred in March 2014.

Failure to implement strategic approaches, however, leads to ongoing transmission of the virus. Endemic transmission is continuing in Afghanistan, Nigeria and Pakistan. Failure to stop polio in these last remaining areas could result in as many as 200 000 new cases every year, within 10 years, all over the world.

Recognizing both the epidemiological opportunity and the significant risks of potential failure, the “Polio Eradication and Endgame Strategic Plan” was developed, in consultation with polio-affected countries, stakeholders, donors, partners and national and international advisory bodies. The new Plan was presented at a Global Vaccine Summit in Abu Dhabi, United Arab Emirates, at the end of April 2013. It is the first plan to eradicate all types of polio disease simultaneously – both due to wild poliovirus and due to vaccine-derived polioviruses.

Future benefits of polio eradication

Once polio is eradicated, the world can celebrate the delivery of a major global public good that will benefit all people equally, no matter where they live. Economic modelling has found that the eradication of polio would save at least US$ 40–50 billion, mostly in low-income countries. Most importantly, success will mean that no child will ever again suffer the terrible effects of lifelong polio-paralysis.


WHO: 1 million new STIs diagnosed each day

WHO

6 June 2019

News release
Geneva, Switzerland

Every day, there are more than 1 million new cases of curable sexually transmitted infections (STIs) among people aged 15-49 years, according to data released today by the World Health Organization. This amounts to more than 376 million new cases annually of four infections – chlamydia, gonorrhoea, trichomoniasis, and syphilis.

“We’re seeing a concerning lack of progress in stopping the spread of sexually transmitted infections worldwide,” said Dr Peter Salama, Executive Director for Universal Health Coverage and the Life-Course at WHO. “This is a wake-up call for a concerted effort to ensure everyone, everywhere can access the services they need to prevent and treat these debilitating diseases.”

Published online by the Bulletin of the World Health Organization, the research shows that among men and women aged 15–49 years, there were 127 million new cases of chlamydia in 2016, 87 million of gonorrhoea, 6.3 million of syphilis and 156 million of trichomoniasis.

These STIs have a profound impact on the health of adults and children worldwide. If untreated, they can lead to serious and chronic health effects that include neurological and cardiovascular disease, infertility, ectopic pregnancy, stillbirths, and increased risk of HIV. They are also associated with significant levels of stigma and domestic violence.

Syphilis alone caused an estimated 200 000 stillbirths and newborn deaths in 2016, making it one of the leading causes of baby loss globally.

About the four STIs

    • Trichomoniasis (or “trich”) is the most common curable STI globally. It is caused by infection by a parasite during sexual intercourse. Chlamydia, syphilis and gonorrhoea are bacterial infections.
    • Symptoms of an STI can include genital lesions, urethral or vaginal discharge, pain when urinating and, in women, bleeding between periods. However, most cases are asymptomatic, meaning people may not be aware they have an infection prior to testing.
    • Chlamydia and gonorrhoea are major causes of pelvic inflammatory disease (PID) and infertility in women. In its later stages, syphilis can cause serious cardiovascular and neurological disease. All four diseases are associated with an increased risk of acquiring and transmitting HIV.
  • Transmission of these diseases during pregnancy can lead to serious consequences for babies including stillbirth, neonatal death, low birth-weight and prematurity, sepsis, blindness, pneumonia, and congenital deformities.

 


The first UN World Food Safety Day to be marked on Friday 7 June

WHO

The first ever celebration of the United Nations World Food Safety Day, to be marked globally on 7 June, aims to strengthen efforts to ensure that the food we eat is safe.

Every year, nearly one in ten people in the world (an estimated 600 million people) fall ill and 420,000 die after eating food contaminated by bacteria, viruses, parasites or chemical substances. Unsafe food also hinders development in many low- and middle-income economies, which lose around US$ 95 billion in productivity associated with illness, disability, and premature death suffered by workers.

World Food Safety Day 2019’s theme is that food safety is everyone’s business. Food safety contributes to food security, human health, economic prosperity, agriculture, market access, tourism and sustainable development.

The UN has designated two of its agencies, the Food and Agriculture Organization (FAO) and the World Health Organization (WHO) to lead efforts in promoting food safety around the world.

FAO and WHO are joining forces to assist countries to prevent, manage and respond to risks along the food supply chain, working with food producers and vendors, regulatory authorities and civil society stakeholders, whether the food is domestically produced or imported.

“Whether you are a farmer, farm supplier, food processor, transporter, marketer or consumer, food safety is your business,” FAO Director-General José Graziano da Silva said. “There is no food security without food safety,” he said.

“Unsafe food kills an estimated 420,000 people every year. These deaths are entirely preventable,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “World Food Safety Day is a unique opportunity to raise awareness about the dangers of unsafe food with governments, producers, handlers and consumers. From farm to plate, we all have a role to play in making food safe.”

Investing in sustainable food systems pays off

FAO and WHO underline the importance of everyone’s access to safe, nutritious and sufficient food, and that safe food is critical to promoting health and ending hunger, two of the primary aims of the Sustainable Development Goals.

Safe food allows for suitable intake of nutrients and contributes to a healthy life. Safe food production improves sustainability by enabling market access and productivity, which drives economic development and poverty alleviation, especially in rural areas.

Investment in consumer food safety education has the potential to reduce foodborne disease and return savings of up to $10 for each dollar invested.

Get involved in World Food Safety Day

Activities around the world for World Food Safety Day aim to inspire action to help prevent, detect and manage foodborne health risks.

The right actions along the food supply chain, from farmers to consumers, as well as good governance and regulations, are essential to food safety.

FAO and WHO have created a new guide to show how everyone can get involved. The guide includes five steps to make a sustained difference to food safety:

  1. Ensure it’s safe. Governments must ensure safe and nutritious food for all.
  2. Grow it safe.  Agriculture and food producers need to adopt good practices.
  3. Keep it safe. Business operators must make sure food is safely transported, stored and prepared.
    1. Check it’s safe. Consumers need access to timely, clear and reliable information about the nutritional and disease risks associated with their food choices.
    2. Team up for safety. Governments, regional economic bodies, UN organizations, development agencies, trade organizations, consumer and producer groups, academic and research institutions and private sector entities must work together on food safety issues.

    Starting in 2019, every 7 June will be a time to highlight the benefits of safe food. World Food Safety Day was adopted by the United Nations General Assembly in December 2018. The process was initiated in 2016 by Costa Rica through the Codex Alimentarius Commission, which is managed by FAO and WHO.


WHO: The world is entering “a new phase” where large outbreaks of deadly diseases like Ebola are a “new normal”

BBC

“……There have been 2,025 cases of Ebola and 1,357 deaths from the virus during the outbreak in the Democratic Republic of Congo……”


MONUSCO Deputy UN Special Representative of the Secretary-General (DSRSG) David Gressly has been appointed UN Emergency Ebola Response Coordinator (EERC) in the Ebola affected areas of the DRC.

WHO

3 May 2019

Statement
Kinshasa/Butembo

Latest numbers as of 22 May 2019

Total cases: 1877
– Confirmed cases: 1789
– Probable cases: 88

Deaths: 1248
– Confirmed: 1160
– Probable: 88

With the Ebola epidemic in the Democratic Republic of the Congo now in its tenth month and the number of new cases increasing in recent weeks, the United Nations announced today measures to strengthen its response and end the outbreak.

The Ebola epidemic has claimed more than 1,200 lives and the risk of spread to other provinces in the eastern Congo as well as neighbouring countries remains very high. A third of those who have fallen ill are children, which is a higher proportion than in previous outbreaks.

Under the leadership of the Government and Congolese communities, with support from the UN and non-governmental organizations (NGOs), the response has contained Ebola in parts of Ituri and North Kivu provinces. But ongoing insecurity and community mistrust in the response continue to hamper access to communities. This is hindering efforts by WHO and the Ministry of Health to detect sick people and ensure access to treatment and vaccination, ultimately leading to more intense Ebola transmission.

In view of the increasingly complex environment, the UN in partnership with the Government and all partners is now strengthening its political engagement and operational support to negotiate access to communities; increasing support for humanitarian coordination; and bolstering preparedness and readiness planning for Goma and surrounding countries. WHO is adapting public health strategies to identify and treat people as quickly as possible; expanding vaccination to reach and protect more people; and redoubling work to end transmission in health facilities.

The UN Secretary-General has established a strengthened coordination and support mechanism in the epicenter of the outbreak, Butembo.

MONUSCO Deputy UN Special Representative of the Secretary-General (DSRSG) David Gressly has been appointed UN Emergency Ebola Response Coordinator (EERC) in the Ebola affected areas of the DRC. Mr. Gressly, who brings a wealth of humanitarian leadership and political and security experience to the role, will report to the SRSG, Leila Zerrougui. He will oversee the coordination of international support for the Ebola response and work to ensure that an enabling environment—particularly security and political—is in place to allow the Ebola response to be even more effective.

Mr. Gressly will work closely with WHO, which will continue to lead all health operations and technical support activities to the Government response to the epidemic. Dr. Ibrahima Socé Fall, Assistant Director-General, Emergency Response, who has been in Butembo since end-March, is leading the WHO response in DRC. WHO will also continue to coordinate public health interventions that are being implemented by other UN partners.

“The Ebola response is working in an operating environment of unprecedented complexity for a public health emergency—insecurity and political protests have led to periodic disruptions in our efforts to fight the disease. Therefore, an enhanced UN-wide response is required to overcome these operating constraints and this includes moving senior leadership and operational decision making to the epicenter of the epidemic in Butembo. We have no time to lose,” said DSRSG Gressly.

WHO’s Dr. Fall said: “This system-wide and international support is exactly what WHO has been calling for. We know that the outbreak response must be owned by the local population, and this new approach reflects what they have asked for: better security for patients and health workers, wider access to vaccination, and a more humane face to the response.” Dr. Fall has been working alongside Dr. Michel Yao, the WHO Ebola Incident Manager who has been in place since August 2018.  In Kinshasa, WHO has also appointed a special representative to the Ebola Response, Dr. Peter Graaff, to coordinate with partners there.

Additional UN measures will bolster the critical work of non-governmental organizations (NGOs) and agencies already on the ground, including UNICEF. Working with NGOs, UNICEF leads community engagement activities; provides psychosocial interventions; and helps prevent infection through water, sanitation and hygiene services.

Financial planning and reporting will also be strengthened and efforts will be accelerated to ensure sustainable and predictable funding required for the Ebola strategic response plan considering the ongoing needs.


UN strengthens Ebola response in Democratic Republic of the Congo

WHO

23 May 2019

Statement
Kinshasa/Butembo

With the Ebola epidemic in the Democratic Republic of the Congo now in its tenth month and the number of new cases increasing in recent weeks, the United Nations announced today measures to strengthen its response and end the outbreak.

The Ebola epidemic has claimed more than 1,200 lives and the risk of spread to other provinces in the eastern Congo as well as neighbouring countries remains very high. A third of those who have fallen ill are children, which is a higher proportion than in previous outbreaks.

Under the leadership of the Government and Congolese communities, with support from the UN and non-governmental organizations (NGOs), the response has contained Ebola in parts of Ituri and North Kivu provinces. But ongoing insecurity and community mistrust in the response continue to hamper access to communities. This is hindering efforts by WHO and the Ministry of Health to detect sick people and ensure access to treatment and vaccination, ultimately leading to more intense Ebola transmission.

In view of the increasingly complex environment, the UN in partnership with the Government and all partners is now strengthening its political engagement and operational support to negotiate access to communities; increasing support for humanitarian coordination; and bolstering preparedness and readiness planning for Goma and surrounding countries. WHO is adapting public health strategies to identify and treat people as quickly as possible; expanding vaccination to reach and protect more people; and redoubling work to end transmission in health facilities.

The UN Secretary-General has established a strengthened coordination and support mechanism in the epicenter of the outbreak, Butembo.

MONUSCO Deputy UN Special Representative of the Secretary-General (DSRSG) David Gressly has been appointed UN Emergency Ebola Response Coordinator (EERC) in the Ebola affected areas of the DRC. Mr. Gressly, who brings a wealth of humanitarian leadership and political and security experience to the role, will report to the SRSG, Leila Zerrougui. He will oversee the coordination of international support for the Ebola response and work to ensure that an enabling environment—particularly security and political—is in place to allow the Ebola response to be even more effective.

Mr. Gressly will work closely with WHO, which will continue to lead all health operations and technical support activities to the Government response to the epidemic. Dr. Ibrahima Socé Fall, Assistant Director-General, Emergency Response, who has been in Butembo since end-March, is leading the WHO response in DRC. WHO will also continue to coordinate public health interventions that are being implemented by other UN partners.

“The Ebola response is working in an operating environment of unprecedented complexity for a public health emergency—insecurity and political protests have led to periodic disruptions in our efforts to fight the disease. Therefore, an enhanced UN-wide response is required to overcome these operating constraints and this includes moving senior leadership and operational decision making to the epicenter of the epidemic in Butembo. We have no time to lose,” said DSRSG Gressly.

WHO’s Dr. Fall said: “This system-wide and international support is exactly what WHO has been calling for. We know that the outbreak response must be owned by the local population, and this new approach reflects what they have asked for: better security for patients and health workers, wider access to vaccination, and a more humane face to the response.” Dr. Fall has been working alongside Dr. Michel Yao, the WHO Ebola Incident Manager who has been in place since August 2018.  In Kinshasa, WHO has also appointed a special representative to the Ebola Response, Dr. Peter Graaff, to coordinate with partners there.

Additional UN measures will bolster the critical work of non-governmental organizations (NGOs) and agencies already on the ground, including UNICEF. Working with NGOs, UNICEF leads community engagement activities; provides psychosocial interventions; and helps prevent infection through water, sanitation and hygiene services.

Financial planning and reporting will also be strengthened and efforts will be accelerated to ensure sustainable and predictable funding required for the Ebola strategic response plan considering the ongoing needs.

 


International Coordinating Group (ICG) on Vaccine Provision

WHO

What is the ICG?

The ICG was established in 1997, following major outbreaks of meningitis in Africa, as a mechanism to manage and coordinate the provision of emergency vaccine supplies and antibiotics to countries during major outbreaks. Working closely with vaccine producers, through WHO and UNICEF, and following disease trends, the ICG monitors its vaccine security global stock levels for cholera, meningitis and yellow fever to ensure availability of sufficient supply to respond to disease outbreaks when they occur.

The ICG brings partners together to improve cooperation and coordination of epidemic preparedness and response. The ICG also works on forecasting vaccine stocks, negotiating vaccine prices through its networks or partners, evaluating interventions and standard protocols for managing diseases.

The ICG’s mission is to:

  • Rapidly deliver vaccines to respond to disease outbreaks;
  • Provide equitable vaccine allocation through careful assessment of risk, based on epidemiological and operational criteria;
  • Coordinate the use of limited amounts of vaccines and essential medicines;
  • Reduce wastage of vaccines and supplies;
  • Advocate for readily available, low-cost vaccines and medicines;
  • Work with manufacturers through UNICEF and WHO to guarantee the availability of vaccine emergency stock supplies at the global levels;
  • Follow standard operating procedures and establish financial mechanisms to purchase emergency vaccine supplies and ensure their sustainability.

Who are ICG’s partners?

The ICG is made up of four member agencies:

International Federation of the Red Cross and Red Crescent Societies (IFRC) – Has strong country presence for community health promotion, local social and resource mobilization and provides support to states during disasters and epidemics.

Médecins sans Frontières (MSF) – An independent, field-based NGO that provides health care to vulnerable populations in emergency settings.

United Nations Children’s Fund (UNICEF) – Conducts wide scale vaccine procurement and shipment, and provides technical support on campaign planning and implementation in country focusing specially on social mobilization and cold chain.

World Health Organization (WHO) – Provides global public health advice and technical support to countries. During outbreaks, WHO focuses on vaccine stockpile management, surveillance, preparedness and response to disease outbreaks.

Additional expertise and technical advice is provided on a case-by- case basis from partners including: Agence de Médecine Preventive in Paris, Epicentre in Paris, GAVI the Vaccine Alliance, WHO Collaborating Centres, the US Centers for Disease Control and the European Community Humanitarian Office (ECHO).

Vaccine manufacturers, vaccine equipment providers and financial donor institutions are also engaged in the ICG operations.

Which vaccine stockpiles are available through the ICG?

ICGs have been established to provide access to vaccines for the following diseases:

Cholera – Since 2013, the ICG for Cholera manages the global stockpile of oral cholera vaccine which was created as an additional tool to help control cholera epidemics. Since July 2013, the ICG has released more than 5 million doses of oral cholera vaccines to affected countries.

Meningitis – The ICG on Vaccine Provision for Epidemic Meningitis Control was established in January 1997, following major outbreaks of meningitis in Africa. Since then, 59 million doses of vaccines were shipped for emergency response in 20 African countries.

Yellow fever – Since 2001, 90 million doses of yellow fever vaccine have been released and shipped to countries facing outbreaks. With vaccine manufacturers as partners in the ICG, a stockpile of 6 million doses has been reserved for outbreak response since May 2016.

How does the ICG decide to release emergency vaccine stockpiles?

Vaccine security stocks can be accessed by ANY country facing an epidemic ANYWHERE in the world, as long as the country’s request fulfills ICG’s criteria for release of vaccine stocks. As a first step, a country must complete and submit a request to the ICG Secretariat using the standard application form

The ICG secretariat at WHO then circulates this request to the partners: UNICEF, Médecins Sans Frontières, the International Federation of the Red Cross, and WHO for review and assessment. Additional requests for information are sent back to the country, if needed. Following a rapid consultation and evaluation process, the decision to release vaccines and other supplies is communicated to the requesting country within 48 hours, once all necessary information has been provided. If approved, UNICEF procures vaccines and injection materials and organizes delivery of vaccines to the country, ideally within 7 days.

Requests are evaluated taking into account the epidemiological situation, vaccination strategy, pre-existing stocks in the country and operational aspects of the epidemic response.

How does the ICG manage, procure and purchase vaccine supply stocks?

The ICG ensures that contingency stocks of vaccines are available to immediately respond to a disease outbreak.

The emergency vaccine stockpiles are held at the manufacturer’s storage facilities until their release is decided by the ICG. UNICEF procures and ships vaccines and supplies on behalf of the ICG. IFRC and MSF support the vaccine logistics and roll out of immunization campaigns on the ground.

Who funds the purchase of the vaccines?

Every year countries experiencing outbreaks use the ICG mechanism to rapidly obtain quantities of high quality vaccine supplies at special prices.

Two different funding mechanisms are used to ensure emergency stockpiles of the three vaccines (yellow fever, meningitis and cholera) managed by the ICG.

  • Gavi, the vaccine alliance, finances ICG’s stockpiles of meningitis, yellow fever and cholera vaccines for Gavi eligible countries.
  • A revolving fund mechanism was established in 2010 to replenish the costs of vaccines and supplies in order to ensure continuous availability of vaccines to non-Gavi eligible countries before the beginning of the next epidemic season. The funds are managed and used based on consensus of the ICG members. The revolving fund ensures that the vaccine supplies are sustained should long term funding shortages occur. The revolving fund is supported by a number of donors and international agencies.

What are the roles and responsibilities of recipient countries of ICG vaccine stockpiles?

The decision to release vaccine stocks is grounded in evidence-based criteria that includes; epidemiological evidence of an outbreak, laboratory confirmation of pathogen, cold chain storage capacity, the country’s demonstrated capacity to conduct a vaccination campaign and an accompanying plan of action for mass vaccination. A country must submit this information in full, in order for its request for emergency vaccine supplies to be accepted within 48 hours.

Once the request for vaccine supplies has been accepted, a process is put in place to ship the vaccines and supplies. Prior to shipment, the recipient country must demonstrate that there is enough cold chain capacity to receive and store the vaccines and supplies. The recipient country must also ensure that funds are fully available for operational costs of the immunization campaign. Additionally, customs and regulatory approvals must be granted and provided to the ICG prior to the shipment of the vaccines and supplies.


The W.H.O. says once again that the Ebola epidemic does not meet the criteria for declaring an international public health emergency.

NYT


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