UT College of Pharmacy and Pharmaceutical Sciences News

Posts Tagged ‘research’

Dr. Tiwari’s Komen grant to find a cure for triple-negative breast cancer

Dr. Tiwari, assistant professor in the College of Pharmacy and Pharmaceutical Sciences Department of Pharmacology and Experimental Therapeutics, received a Komen grant for his research on drug-resistant triple-negative breast cancer, one of the most aggressive and difficult to treat cancers.

Click image below to see video from WTOL’s broadcast.


NIH Award for Breast Cancer Research

Dr. L.M. Viranga Tillekeratne

Dr. L. M. Viranga Tillekeratne, associate professor of Medicinal and Biological Chemistry, received his first R15 award as a primary investigator from the National Institutes of Health. The award, in the amount of $449,000, will support graduate and undergraduate learning.
NIH Grant Number: 1 R15 CA213185-01A1
Principal Investigator: Tillekeratne, Viranga
Project Title: Novel Small Molecule Ferroptotic Compounds to Target Mesenchymal Breast Cancer and Breast Cancer Stem Cells
Award Issue Date: 12/25/2017 for $449,000

Dr. AbouAlaiwi receives NIH Award

photo: Dean Early congratulates Dr. AbouAlaiwi

Dean Early congratulates Dr. AbouAlaiwi

Dr. Wissam AbouAlaiwi, an Assistant Professor in the Department of Pharmacology and Experimental Therapeutics, received an R15 award as a primary investigator from the National Institutes of Health. The award, in the amount of $379,000, will support graduate and undergraduate learning in Dr. AbouAlaiwi’s lab, where he researches Polycystic Kidney Disease, Cardiovascular Disease and Hypertension, and Primary Cilia function in Cell Division and Cell Cycle Regulation.

International Conference on Emerging Healthcare Materials and Advancement in Toxicology 2016

Emerging HealthCare Materials & Advancement in Toxicology, 1-3 September 2016, Radisson Hotel, Health Sciences Campus, The University of Toledo, Toledo, Ohio

ECAT Conference participants

ECAT Conference participants

An International Conference on Emerging Healthcare Materials and Advancement in Toxicology 2016 was held at Radisson Hotel, The University of Toledo Health Science Campus, Toledo, Ohio, USA, from September 1 – 3, 2016. The conference was organized by Dr. Zahoor A. Shah and Dr. Frederick E. Williams from College of Pharmacy and Pharmaceutical Sciences in collaboration with Dr. Iqbal Ahmad, The University of Manchester, UK.

This conference was the first of its kind focused on emerging healthcare materials and advancements in toxicology. The city of Toledo was selected due to its proximity to big cities like Detroit, Cleveland, Columbus and Ann Arbor. The main focus of this conference was to bring researchers from academia, industry, government and non-governmental organizations onto one platform to discuss the emerging research on nanotechnology and healthcare medicine and its effects on human health. This opportunity facilitated new collaborations and networking benefits to researchers working and studying hard to make healthy use of nanotechnology. Imminent scientists/researchers across the country participated in the conference and the key note/distinguished and invited speakers list is below.

OPENING PLENARY LECTURE: ROBERT L. TANGUAY, Distinguished Professor of Molecular Toxicology Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR.

TITLE: Rapid In Vivo Assessment of the Nano/Bio Interface to Help Develop Safer Nanomaterials.

DISTINGUISHED LECTURE: MARK BANASZAK HOLL, Professor of Chemistry; Director of Macromolecular Science and Engineering, College of Engineering, University of Michigan, An Arbor, MI

TITLE: Fluorescent Materials For Biological Imaging.



JOHN P. WISE, Professor of Pharmacology and Toxicology, School of Medicine, University of Louisville. Louisville, KY

TITLE:  Of Whales and Men:  Lessons Learned about Global Pollution from Great Whales.

MICHAEL CARVAN, Professor, School of Freshwater Sciences, University of Wisconsin, Milwaukee, IL

TITLE: Developmental Methylmercury Exposure Leads to Transgenerational Adult Neurobehavioral Defects—Using Zebrafish to Understand Mechanism.

YANG H. YUN, Associate Professor of Biomedical Engineering, College of Engineering, The University of Akron, Akron, OH

TITLE: The Application of L-Tyrosine Polyphosphate in Nanomedicine.

MOHAMMED O. ALJAHDALI, Professor of Ecological Physiology, King Abdulaziz University Rabigh, Saudi Arabia.

TITLE: Sesamin Ameliorates STZ Induced Free Radical Mediated Oxidative Stress in Diabetic Retina.

ANDREW P. AULT, Assistant Professor of Environmental Health Sciences and Chemistry, School of Public Health, University of Michigan, An Arbor, MI

TITLE: Rapid Size and pH-Dependent Modification of Silver Nanoparticles in Simulated Gastrointestinal System

KATSUHISA KUROGI, Assistant Professor, University of Miyazaki, Japan

TITLE: Investigation of the Metabolism of Steroids-Related Compounds Through Sulfation Using the Zebrafish.

TARIQ HAMID, Assistant Professor, School, Cardiovascular Disease Center, School of Medicine, University of Alabama, Birmingham, AL

TITLE: Anticancer Drug Imatinib, Stem Cells and Myocardial Regeneration.

JERRY NESAMONY, Associate Professor of Pharmaceutics, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH

TITLE: Exploring Multiple Strategies to Develop Nanostructured Systems For Use in Drug Delivery.

SCOTT HALL, Assistant Professor, Assistant Professor of Pharmacology and Experimental Therapeutics, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH


Research Excellence Award for Dr. Tiwari

Dr. Amit Tiwari, assistant professor in the Department of Pharmacology and Experimental Therapeutics, recently spent some time in India as a visiting scientist and professor at Rajiv Gandhi Prodyogik Vishwavidyalaya (RGPV). RGPV is the world’s 28th largest university, with a student population of over 260,000. Dr. Tiwari’s visit was part of a research collaboration in the area of oncology drug discovery, which attracted the attention of the national media and several university and government officials, including the president of the university and the Governor of State, Chief Secretary, Principal Secretary of the State, Education Minister and former Home Minister of the State.

During his time at RGPV, Dr. Tiwari received an Outstanding Scientist award for Excellence in Innovative Research.

Rising in the Ranks

Recently, the U.S. News and World Report updated its rankings of pharmacy schools. Always highly regarded, the College of Pharmacy and Pharmaceutical Sciences was first ranked by this publication in 2012 as a result of concerted efforts by the college to expand external communications and spread the word about our programs and people.

The newest rankings show an improvement for the college, from number 62 among over 80 ranked colleges to number 60 of over 100 ranked schools, indicating the persistently high regard for the program, even in a time of fiscal austerity.

The College continues to engage in the activities that moved it onto the lists of ranked colleges through its learners, faculty and staff and their efforts in academics and service in key roles in state and national pharmacy organizations.  The college’s complex and comprehensive program of twelve curricula pioneered the Pharmacy Summer Camp as a recruitment tool for pharmacy and the pharmaceutical sciences.  An added offering is the teaching certificate for pharmacy residents.

The College of Pharmacy and Pharmaceutical Sciences attracts high achieving learners to its BS in Pharmaceutical Sciences majors in cosmetic science and formulation design, pharmacology and toxicology, pharmaceutics, medicinal chemistry, and pharmacy administration (with a minor in business).  Future practitioners enroll in the college’s highly competitive PharmD program and study in the clinics and pharmacies of the University of Toledo Medical Center.  Learners who are focused on research continue in the MS and PhD programs, the latter of which include medicinal chemistry and experimental therapeutics.  Students have the opportunity to earn dual-degrees, including the BSPS/MS degree in medicinal chemistry, the PharmD/MS in health outcomes and socioeconomic sciences or the PharmD/PhD in medicinal chemistry.  The PharmD/MBA is the college’s newest dual-degree program. Learners also enhance their clinical skills in the PGY1, PGY2, or Kroger Community Pharmacy residency programs.

Open House: Shimadzu Laboratory for Pharmaceutical Research Excellence

The University of Toledo College of Pharmacy and Pharmaceutical Sciences cordially invites you to attend the opening of the Shimadzu Laboratory for Pharmaceutical Research Excellence.   The open house will be held on Thursday, January 28, 2016, beginning at 12 o’ clock noon.  You will have the opportunity to see new acquisitions made by the University of Toledo College of Pharmacy and Pharmaceutical Sciences from Shimadzu Scientific Instruments and hear more details of our growing partnership.  In addition, Dr. Richard van Breemen, Professor of Medical Chemistry and Pharmacognosy and Director of the UIC/NIH Center for Botanical Dietary Supplements Research at the University of Illinois College of Pharmacy, will give a scientific talk to highlight the capabilities of the instrumentation acquired.

Shimadzu Scientific Instruments, a subsidiary of Shimadzu Corporation, is devoted to the education and training of the next generation of scientists and the growth of the scientific enterprise in Northwest Ohio and Southeast Michigan.  Through this partnership, state-of-the-art equipment for pharmaceutical analysis will be available to students, faculty and members of the corporate sector, all with the support of trained and knowledgeable experts in the area of pharmaceutical research.

Please RSVP to Cynthia Tierney, CYNTHIA.TIERNEY@utoledo.edu, if you would like to attend this event.  Refreshments will be served.

Shimadzu flyer

UT Health’s Dr. Sari comments on buprenorphine

Just months ago, the Ohio legislature approved the use of buprenorphine, an ingredient in the drug Suboxone, for the treatment of opioid dependence. Dr. Youssef Sari commented on the use and safety of this medication in an interview on WTOL 11.

Dr. Sari is an associate professor in the Department of Pharmacology and Experimental Therapeutics. Visit his faculty page for more information about his research.

One Step Closer to a Cure

arantesVandressa Arantes, as part of the Brazilian Scientific Mobility Program, completed her summer research internship in Dr. Tiwari’s Cancer Chemotherapy Laboratory in the Department of Pharmacology and Experimental Therapeutics. Vandressa was a part of drug-discovery team in Dr. Tiwari’s lab. The team evaluates the anticancer activity of a novel class of targeted tyrosine kinase inhibitors (TKIs) belonging to the quinazoline class. Their target-based approach focuses on compounds that are designed and synthesized to work against ‘resistant’ solid tumors. These TKIs are designed ensure maximum effects of chemotherapy with minimal side-effects.

Vandressa spent her summer looking at the effects of a series of novel compounds on a panel of resistant and metastatic breast, colorectal and prostate cancer cell lines and comparing their effects to their normal counterparts.

To learn more about Dr. Tiwari’s work, visit his faculty web page. His lab is looking for undergraduate students who are interested in conducting research on these exciting anti-cancer drugs.

Learning outside the Book

Jeremy Canfield photo

Jeremy Canfield, BSPS ’15, valedictorian of the 2015 B.S. in Pharmaceutical Sciences class, shares his advice on learning beyond the pages of the textbook.

Throughout my college career, I have learned many valuable lessons, both inside and outside of the classroom. I found it is extremely important to manage your time wisely and discipline yourself because everything you do in college is for your own benefit.

When I first started my journey here at Toledo, I didn’t know what to expect. I was excited, but very nervous to begin this new chapter in my life. It was hard starting over again and meeting new people, but I got through it just as you all did. From our PP1 year all the way to our P2 year, it may have been hard, but we made it. After everything, The College of Pharmacy Pharmaceutical Sciences has increased my passion for the pharmaceutical sciences and prepared me for a career. I gained a lot of hands on experience which I found to be more valuable than anything I could’ve read about in a book.

Over the past three years, one thing I found out about college is that in order to have the most enjoyable time, you have to get out of your comfort zone. That wasn’t easy for me, but with the help of some good friends, I started to try more new things. I realized college isn’t just about the courses you take and how you do on exams, it’s also about the people you meet and the experiences you have.

It’s hard to believe that it’s coming to an end already. But just as we began a new chapter when we started here at Toledo, today is the beginning of the next chapter in our lives. Whether we are continuing school or entering into the work force, we are all well prepared for what lies ahead.