Global & Disaster Medicine

Archive for the ‘Dengue’ Category

Mosquito-disseminated pyriproxyfen (PPF), a potent juvenile-killing insecticide, has potential to block mosquito-borne virus transmission citywide


Abad-Franch F, Zamora-Perea E, Luz SLB (2017) Mosquito-Disseminated Insecticide for Citywide Vector Control and Its Potential to Block Arbovirus Epidemics: Entomological Observations and Modeling Results from Amazonian Brazil. PLoS Med 14(1): e1002213. doi:10.1371/journal.pmed.1002213




In 2013 there were a total of 58.40 million symptomatic dengue virus infections including 13 586 fatal cases, and that the total annual global cost of dengue illness was US$8·9 billion.

The Lancet

Image: Lab Confirmed cases of Dengue in South America

Image: Dengue in the world



Group from Argentina developes a plastic ovitrap, a small cup made from low-density polyethylene that has been infused with pyriproxyfen to knock off Aedes mosquitoes

Aedes Traps


Biological and Chemical Characterization of a New Larvicide Ovitrap Made of Plastic With Pyriproxyfen Incorporated for Aedes aegypti (Diptera: Culicidae) Control

Brazil: Zika isn’t the only emergency. 2 other mosquito-borne viruses are spiking: Dengue and CHIKV. Meanwhile, the country is going through a massive economic and political crisis as well, facing one of the worst recessions in its history.


Recife:  “….New cases of microcephaly are dramatically down. Last November, Recife registered 125 cases. But since the beginning of this year, the numbers have hovered around 25 a month……[T]he decline was expected: Women giving birth this spring would have become pregnant during the cooler winter period when there were fewer mosquitoes around to transmit Zika……”

Fighting the Aedes mosquito

Graphic: Mosquito prevention starts with you

Kids with Dengue


Symptomatic Dengue in Children in 10 Asian and Latin American Countries

Maïna L’Azou, M.Sc., Annick Moureau, M.Sc., Elsa Sarti, Ph.D., Joshua Nealon, M.Sc., Betzana Zambrano, M.D., T. Anh Wartel, M.D., Luis Villar, M.D., Maria R.Z. Capeding, M.D., and R. Leon Ochiai, Ph.D., for the CYD14 and CYD15 Primary Study Groups*

N Engl J Med 2016; 374:1155-1166

March 24, 2016

DOI: 10.1056/NEJMoa1503877

“…..The incidence of dengue hemorrhagic fever was less than 0.3 episodes per 100 person-years in each cohort. The percentage of VCD episodes requiring hospitalization was 19.1% in the Asian cohort and 11.1% in the Latin American cohort. In comparable age groups (9 to 12 years and 13 to 16 years), the burden of dengue was higher in Asia than in Latin America……”

Zika is just one of a growing number of continent-jumping diseases carried by mosquitoes and threatening swathes of humanity.






The Aedes mosquitoes that transmit the virus on Puerto Rico have developed resistance to permethrin.




Latest Research: Evidence suggests that symptomatic dengue during pregnancy might be associated with fetal adverse outcomes.


**  Preterm birth and low birth weight were the most common adverse outcomes in mothers who contracted dengue.



Colombia is said to have made progress on what could be an innovative way of controlling the disease. A tropical disease specialist at the University of Antioquia states scientists there had successfully bred a mosquito that was resistant to Zika, dengue, chikungunya and yellow fever.

NY Times


“…..To create the strain, Dr. Vélez infected mosquitoes with bacteria that block the insects from picking up the virus. When the mosquitoes breed with ones that are susceptible to the disease, their progeny are shielded.

“The results are encouraging,” Dr. Vélez said, citing a recent pilot project near Medellín in which 80 percent of mosquitoes were rendered unable to transmit Zika…….”



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