Global & Disaster Medicine

Archive for the ‘Ebola’ Category

The Democratic Republic of Congo (DRC) health ministry announced that it has received reports of 25 fever cases with symptoms similar to Ebola in the eastern part of the country.

DRC Ministry of Health

MIN SANTE – PRESS RELEASE – JULY 30, 2018
Reported fever cases in Mabalako Health Zone, North Kivu Province
Kinshasa, July 30, 2018 – This Saturday, July 28, 2018, the Provincial Health Division of North Kivu has notified 25 cases of fever in the health area of ​​Mangina, located about 30 km southwest of the city of Blessed. Samples have been collected and are being sent to Kinshasa for analysis by the National Institute for Biomedical Research (INRB).

An investigative team from the General Directorate for the Fight Against Disease (DGLM) composed of three experts, including two epidemiologists and a biologist, will arrive in Beni as early as Tuesday, July 31, 2018 to support the provincial team.

The Ministry of Health instructed health professionals in the province to respect individual protection measures. In addition, the Ministry invites the population in the areas concerned to remain calm, vigilant and to respect the hygiene measures, in particular the regular washing of the hands.

END

Ebola outbreak in DRC ends

WHO

Ebola outbreak in DRC ends: WHO calls for international efforts to stop other deadly outbreaks in the country

24 July 2018

News Release
KINSHASA/GENEVA

Today marks the end of the ninth outbreak of Ebola in the Democratic Republic of the Congo (DRC). The World Health Organization (WHO) congratulates the country and all those involved in ending the outbreak, while urging them to extend this success to combatting other diseases in DRC.

WHO Director-General, Dr Tedros Adhanom Ghebreyesus, and Regional Director for Africa, Dr Matshidiso Moeti, joined Minister of Health Dr Oly Ilunga for the announcement in Kinshasa.

“The outbreak was contained due to the tireless efforts of local teams, the support of partners, the generosity of donors, and the effective leadership of the Ministry of Health. That kind of leadership, allied with strong collaboration between partners, saves lives,” said Dr Tedros.

Unlike previous Ebola outbreaks in the country, this one involved four separate locations, including an urban centre with river connections to the capital and to neighbouring countries, as well as remote rainforest villages. There were initial concerns that the disease could spread to other parts of DRC, and to neighbouring countries.

Within hours of the outbreak being declared on 8 May, WHO released US$2 million from its Contingency Fund for Emergencies, deployed a team to augment capacity in the field, and activated an emergency incident management system.

“WHO moved quickly and efficiently,” said Dr Moeti, “We also demonstrated the tremendous capacity of the African region. More than three-quarters of the 360 people deployed to respond came from within the region. Dozens of experts from Guinea spent weeks leading Ebola vaccination efforts here, transferring expertise which will enable the DRC to mount an effective response both within its borders and beyond.”

Dr Tedros urged the DRC Government and the international community to build on the positive momentum generated by the quick containment of the Ebola outbreak.

“This effective response to Ebola should make the Government and partners confident that other major outbreaks affecting the country such as cholera and polio can also be tackled,” said Dr Tedros. “We must continue to work together, investing in strengthened preparedness and access to healthcare for the most vulnerable.”

  • WHO’s rapid response and scale up of operations in the DRC was funded by a total of US$4 million disbursement from the WHO Contingency Fund for Emergencies (CFE).
  • WHO and partners appealed for US$57 million to stop the spread of Ebola. The total funds received by all partners, as tracked by OCHA, amount to US$63 million.

A case of Ebola disease in a Liberian woman in 2015 who had recovered from the disease

The Lancet

Persistence of Ebola virus after the end of widespread transmission in Liberia: an outbreak report

Dokubo, Emily Kainne et al.
The Lancet Infectious Diseases

“…..Based on serology and epidemiological and genomic data, the most plausible scenario is that a female case in the November, 2015, cluster survived Ebola virus disease in 2014, had viral persistence or recurrent disease, and transmitted the virus to three family members a year later...…”


Ebola & severe neurologic sequelae among survivors

CDC-EID

Howlett PJ, Walder A, Lisk DR, Fitzgerald F, Sevalie S, Lado M, et al. Case series of severe neurologic sequelae of Ebola virus disease during epidemic, Freetown, Sierra Leone. Emerg Infect Dis. 2018 Aug [date cited]. https://doi.org/10.3201/eid2408.171367

“….We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting neurologic criteria were invited from a cohort of 361 EVD survivors to attend a preliminary clinic. Those whose severe neurologic features were documented in the preliminary clinic were referred for neurology specialist evaluation, ophthalmology examination, and psychiatric assessment. Of 35 survivors with neurologic sequelae, 13 had migraine headache, 2 stroke, 2 peripheral sensory neuropathy, and 2 peripheral nerve lesions. Of brain computed tomography scans of 17 patients, 3 showed cerebral and/or cerebellar atrophy and 2 confirmed strokes. Sixteen patients required mental health followup; psychiatric disorders were diagnosed in 5. The 10 patients who experienced greatest disability had co-existing physical and mental health conditions. EVD survivors may have ongoing central and peripheral nervous system disorders, including previously unrecognized migraine headaches and stroke.….”

 


An Ebola outbreak in the Democratic Republic of Congo has been declared “largely contained” by the WHO.

NY Times

  • More than 3,200 people were vaccinated in Congo
  • None of those vaccinated became ill

    53 cases that were laboratory-confirmed or considered “probable” had been detected, and 29 patients had died

    More than 1,500 contacts of the confirmed or probable cases had been followed for 21 days and had not displayed Ebola symptoms, the W.H.O. said. Three weeks is considered the maximum incubation period for the infection.

    The outbreak will not officially be declared over until at least one more 21-day incubation period has passed

    Vue partielle de l’Unité de virologie et de l'immunologie Moléculaires de l'Institut national de recherche biomédicale (INRB) de Kinshasa. OMS/Eugene Kabambi


Scientists have captured the clearest and most detailed image yet of Zika that could contribute to the development of more effective vaccines and treatments to combat the virus.

NY Times

This is a transmission electron microscopic (TEM) image of Zika virus, grown in LLC-MK2 culture cells, which is a member of the family Flaviviridae. Virus particles are 40 nm in diameter, with an outer envelope, and an inner dense core. Also note the smooth membrane vesicles, which are known to be the replication complex for this virus.

Credit:  CDC/Goldsmith, Rollin

 


Ebola in the DRC: SitRep, 6/18/18

The epidemiological situation of the Ebola Virus Disease dated June 18, 2018 :
  • A total of 60 cases of haemorrhagic fever were reported in the region, including 38 confirmed, 14 probable and 8 suspected .
  • 5 new suspicious cases in Iboko
  • 7 samples were negative
  • 24 people have been cured of Ebola Virus Disease since the beginning of the epidemic
  • No deaths reported so far
  • No new cases confirmed

Ebola and the bush meat trade

CTV

“…….For 25 years, Patrick Matondo has earned a living buying and selling monkeys, bats and other animals popularly known as bush meat along the Congo River. Standing on the riverbank in Mbandaka, a city affected by the deadly new outbreak of the Ebola virus, the father of five said that for the first time he’s worried he won’t be able to support his family.

“Since Ebola was declared, business has decreased by almost half. It’s really, really bad,” the 47-year-old said, hanging his head…..”


DRC & Ebola: the overall outbreak total to 59 cases, which include 38 confirmed illnesses, 14 probable, and 7 suspected with no new deaths were reported, keeping the fatality count at 28.

WHO

 


14 more suspected cases have been reported in the Democratic Republic of Congo (DRC) Ebola outbreak

PS-Twitter

Peter Salama:  Deputy Director-General for Emergency Preparedness and Response

DRC update as of 9 June:
38 confirmed cases
14 probable cases
14 suspected cases
Total: 66 cases, including 28 deaths

New developments:
3 new suspected cases
11 suspected cases from 8 June reported today
12 samples tested negative
1 death in a known confirmed case


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