Global & Disaster Medicine

M 4.3 – TYRRHENIAN SEA – 2017-08-21 18:57:52 UTC


Candida auris is an emerging fungus that presents a serious global health threat.

CDC

August 21, 2017: Case Count Updated as of July 31, 2017

Candida auris is an emerging fungus that presents a serious global health threat. Healthcare facilities in several countries have reported that C. auris has caused severe illness in hospitalized patients. Some strains of C. auris are resistant to all three major classes of antifungal drugs. This type of multidrug resistance has not been seen before in other species of Candida. Also of concern, C. auris can persist on surfaces in healthcare environments and spread between patients in healthcare facilities. CDC has developed identification(https://www.cdc.gov/fungal/diseases/candidiasis/recommendations.html), treatment(https://www.cdc.gov/fungal/diseases/candidiasis/c-auris-treatment.html), and infection control(https://www.cdc.gov/fungal/diseases/candidiasis/c-auris-infection-control.html) recommendations to help prevent the spread of C. auris.

CDC encourages all U.S. laboratory staff who identify C. auris to notify their state or local public health authorities and CDC at candidaauris@cdc.gov.

Candida auris cases in the United States

Location represents the state of C. auris specimen collection. The case counts displayed reflect clinical cases of C. auris (i.e., based on specimens collected in the normal course of care). They do not include patients who screened for presence of C. auris colonization. C. auris has been isolated from an additional 120 patients from healthcare facilities in 4 states where clinical cases were detected.  This map will be updated monthly.

Publications

CDC Publications:
Candida auris reported from other countries:

India

Israel

Japan

Kuwait

South Afria

South Korea

Spain

United Kingdom

Venezuela

Recommendations from other countries
Laboratory aspects of Candida auris
Other publications

Typhoon Hato, a maximum category 10 storm, slammed into Hong Kong killing 3 and injuring at least 30.

NY Daily News


More than 30 people were injured when an inbound train crashed into another that was parked at a station in suburban Philadelphia.

NY Daily News

Philadelphia, Pennsylvania

NASA:  Philadelphia

 


8/21/1986: An eruption of lethal gas from Lake Nyos in Cameroon kills nearly 2,000 people and wipes out four villages.

History Channel

 


French officials reported two confirmed local cases of indigenous CHIKV in southern France.

ECDC

“….As of 17 August 2017, France reported two confirmed autochthonous chikungunya cases in the Var district, in southern France. The first case who lives in Cannet-des-Maures in Var district and works in Alpes-Maritimes district had onset of symptoms on 1 August. The diagnostic was confirmed by two PCR tests on 9 an 11 August. The second case, a 67-year-old neighbour of the first case, had onset of symptoms on 8 August and was confirmed on 14 August…..”


There is evidence to support that Ebola virus may have a direct role in muscular damage and imbalance of the coagulation system.

Clinical Infectious Diseases

“….Though the study provided no evidence that Ebola affected the kidneys, kidney damage is often seen in Ebola patients.
The authors said this was because Ebola viremia was strongly related to evidence of rhabdomyolysis, the rapid breakdown of muscles, which stresses the kidneys….”

 


Researchers followed 27 Ebola survivors in Sierra Leone for 1 year after diagnosis and found they were seven times more likely than their close contacts to report a disability.

Clinical Infectious Diseases

“….Major limitations in vision, mobility, cognition, and affect were observed in survivors one year following the 2014-6 Ebola outbreak, highlighting the need for long-term rehabilitation…..”


Neurological complications associated with Zika virus in adults in Brazil

Eureka News Alert

“…..A new article published by JAMA Neurology reports on a study of hospitalized adult patients with new-onset neurologic syndromes who were evaluated for Zika virus infection.

The single-center study of 40 patients, include 29 with Guillain-Barré syndrome (GBS), seven with encephalitis, three with transverse myelitis and one with newly diagnosed chronic inflammatory demyelinating polyneuropathy.

Of those 40 patients, 35 (88 percent) had evidence of recent Zika virus infection in the serum (blood) or cerebrospinal fluid, according to the results. Of the patients who were positive for Zika virus infection, 27 had GBS, five had encephalitis, two had transverse myelitis and one had chronic inflammatory demyelinating polyneuropathy, according to the results…..”


India: An in-hospital mortality rate of nearly 70% was observed in patients with dual colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections (CCRKP BSI)

AJIC

  • 75 patients with colistin-resistant Klebsiella pneumoniae bloodstream infections were examined.
  • Observed:  A high in-hospital mortality rate of 69.3% (52/75 patients).
  • Among the 52 patients who did not survive, 28 patients died within 48 hours of bacteremia.

Clinical outcome of dual colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections: A single-center retrospective study of 75 cases in India

Kaur, Amarjeet et al.

American Journal of Infection Control

 


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