Global & Disaster Medicine

Archive for the ‘Ebola’ Category

Three new Ebola cases confirmed, raising total to 3,178

“The steady trickle of new Ebola cases in the Democratic Republic of the Congo (DRC) continued today, with the World Health Organization (WHO) dashboard showing three new cases and three new fatalities.

The outbreak total now stands at 3,178 cases, with 2,122 deaths, and 520 suspected cases under investigation…..”

WHO Ebola dashboard


The WHO is getting nervous about Ebola in Tanzania and no one notifying them about it.

WHO

“……On 10 September 2019, through its regular event-based surveillance process, WHO was made aware of unofficial reports regarding the death of a person with suspected Ebola Virus disease (EVD) case in Dar es Salaam, United Republic of Tanzania. The identified contacts of the deceased were unofficially reported to be quarantined in various sites in the country. Under the IHR Articles 9 and 10, WHO immediately sent a verification request to the National IHR Focal Point (NFP) of the country.

On 11 September, through its regular event-based surveillance process, WHO was made aware of unofficial reports that a RT-PCR test performed at the Tanzanian National Health Laboratory was positive for EVD for this patient. On the same day, WHO received unofficial reports regarding another suspected EVD case in Mwanza, located in the northern region of the United Republic of Tanzania, who later tested negative for EVD. WHO continued to reach out under the IHR to the health authorities of the United Republic of Tanzania to verify these signals.

On 12 September 2019, WHO was informed by unofficial sources of a 27-year-old patient suspected of EVD admitted in a hospital of Dar es Salaam without further information regarding laboratory tests and results

Despite several requests, WHO did not receive further details of any of these cases from Tanzanian authorities…..”


Ebola virus disease – Democratic Republic of the Congo Disease outbreak news: Update (12 September 2019)

“……As of 10 September, a total of 3091 EVD cases were reported, including 2980 confirmed and 111 probable cases, of which 2074 cases died (overall case fatality ratio 67%). Of the total confirmed and probable cases, 56% (1737) were female, 29% (886) were children aged less than 18 years, and 5% (157) were health workers…….”

 


Subsequent mortality in survivors of Ebola virus disease in Guinea: a nationwide retrospective cohort study

Subsequent mortality in survivors of Ebola virus disease in Guinea: a nationwide retrospective cohort study

Published:September 04, 2019DOI:https://doi.org/10.1016/S1473-3099(19)30313-5

“Findings

….Of the 1270 survivors of Ebola virus disease who were discharged from Ebola treatment units in Guinea, information was retrieved for 1130 (89%). Compared with the general Guinean population, survivors of Ebola virus disease had a more than five-times increased risk of mortality up to Dec 31, 2015 (age-standardised mortality ratio 5·2 [95% CI 4·0–6·8]), a mean of 1 year of follow-up after discharge. Thereafter (ie, from Jan 1–Sept 30, 2016), mortality did not differ between survivors of Ebola virus disease and the general population. (0·6 [95% CI 0·2–1·4]). Overall, 59 deaths were reported, and the cause of death was tentatively attributed to renal failure in 37 cases, mostly on the basis of reported anuria. Longer stays (ie, equal to or longer than the median stay) in Ebola treatment units were associated with an increased risk of late death compared with shorter stays (adjusted hazard ratio 2·62 [95% CI 1·43–4·79]).

Interpretation

Mortality was high in people who recovered from Ebola virus disease and were discharged from Ebola treatment units in Guinea. The finding that survivors who were hospitalised for longer during primary infection had an increased risk of death, could help to guide current and future survivors’ programmes and in the prioritisation of funds in resource-constrained settings. The role of renal failure in late deaths after recovery from Ebola virus disease should be investigated….”

WHO: 5 new confirmed cases of Ebola, raising the outbreak total to 3,054, with 444 suspected cases under investigation plus there were also 5 additional deaths noted, raising the fatality total to 2,050.

WHO

 

 


WHO: 10 new cases of Ebola have been confirmed in the Democratic Republic of the Congo (DRC), raising the outbreak total to 2,852, and 380 suspected cases are still under investigation.

WHO


A trial of two Ebola drugs showed significantly improved survival rates

BBC

“……Four drugs were trialled on patients in the Democratic Republic of Congo, where there is a major outbreak of the virus.

More than 90% of infected people can survive if treated early with the most effective drugs…….”


The health minister in the Democratic Republic of Congo has resigned in protest at the handling of the Ebola outbreak

BBC

“……In his letter to Félix Tshisekedi, he criticised the decision to remove him as head of the Ebola response team, and replace him by a committee “under your direct supervision”.

He said members of that committee had interfered with his work in recent months.

He also condemned “strong pressure exercised in recent months” to use a new Ebola vaccine advocated by some aid agencies and donors……”

  • More than 2,500 people have been infected
  • 2/3 of them have died.
  • It took 224 days for the number of cases to reach 1,000
  • It took just 71 days to reach 2,000.
  • About 12 new cases are being reported every day.

Three previous Ebola outbreaks have demonstrated how a response can succeed — or how, in an atmosphere of suspicion, it can go badly wrong.

NYT

The Mbandaka outbreak: “The outbreak just before the current one ushered in a new era in the war against Ebola: a new Merck vaccine stopped the outbreak in just three months, after only 33 deaths……”

The West African outbreak: “History’s worst Ebola outbreak was the one that began in West Africa in late 2013 and whose last flare-ups were not snuffed out until early 2016. The outbreak infected over 28,000 people and killed over 11,000……”

The outbreak named ‘Ebola’:   The 1976 outbreak that gave the virus its name also created the air of otherworldly terror that surrounds it. Most of the 318 cases and 280 deaths were in Yambuku, in the north of what was then Zaire…..”


WHO’s director-general, Tedros Adhanom Ghebreyesus, PhD, declared that the Democratic Republic of the Congo’s Ebola outbreak is a public health emergency of international concern (PHEIC).

WHO

17 July 2019

News release
Geneva

WHO Director-General Dr. Tedros Adhanom Ghebreyesus today declared the Ebola virus disease (EVD) outbreak in the Democratic Republic of the Congo (DRC) a Public Health Emergency of International Concern (PHEIC).

“It is time for the world to take notice and redouble our efforts. We need to work together in solidarity with the DRC to end this outbreak and build a better health system,” said Dr. Tedros. “Extraordinary work has been done for almost a year under the most difficult circumstances. We all owe it to these responders — coming from not just WHO but also government, partners and communities — to shoulder more of the burden.”

The declaration followed a meeting of the International Health Regulations Emergency Committee for EVD in the DRC. The Committee cited recent developments in the outbreak in making its recommendation, including the first confirmed case in Goma, a city of almost two million people on the border with Rwanda, and the gateway to the rest of DRC and the world.

This was the fourth meeting of the Emergency Committee since the outbreak was declared on 1 August 2018.

The Committee expressed disappointment about delays in funding which have constrained the response. They also reinforced the need to protect livelihoods of the people most affected by the outbreak by keeping transport routes and borders open. It is essential to avoid the punitive economic consequences of travel and trade restrictions on affected communities.

“It is important that the world follows these recommendations. It is also crucial that states do not use the PHEIC as an excuse to impose trade or travel restrictions, which would have a negative impact on the response and on the lives and livelihoods of people in the region,” said Professor Robert Steffen, chair of the Emergency Committee.

Since it was declared almost a year ago the outbreak has been classified as a level 3 emergency – the most serious – by WHO, triggering the highest level of mobilization from WHO. The UN has also recognized the seriousness of the emergency by activating the Humanitarian System-wide Scale-Up to support the Ebola response.

In recommending a PHEIC the committee made specific recommendations related to this outbreak.

“This is about mothers, fathers and children – too often entire families are stricken. At the heart of this are communities and individual tragedies,” said Dr. Tedros. “The PHEIC should not be used to stigmatize or penalize the very people who are most in need of our help.”


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