Global & Disaster Medicine

Konzo: An irreversible upper-motor neuron disorder affecting children dependent on bitter cassava for food.


Cognitive and motor performance in Congolese children with konzo during 4 years of follow-up: a longitudinal analysis.  Boivin, Michael J et al.  The Lancet Global Health , Volume 5 , Issue 9 , e936 – e947

“…..Motor and cognitive performance continues to be significantly impaired in boys with konzo at 2-year follow-up compared with boys without konzo. Because these impairments are associated in part with exposure to poorly processed cassava as measured by urinary thiocyanate, interventions are urgently needed to ensure improved processing of cassava to detoxify this food source…..”

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