** Dengue’s global burden: The dengue incidence has increased six-fold from 1990 to 2013
February 15th, 2016“…..We estimated an average of 9221 dengue deaths per year between 1990 and 2013, increasing from a low of 8277 (95% uncertainty estimate 5353–10 649) in 1992, to a peak of 11 302 (6790–13 722) in 2010. This yielded a total of 576 900 (330 000–701 200) years of life lost to premature mortality attributable to dengue in 2013. The incidence of dengue increased greatly between 1990 and 2013, with the number of cases more than doubling every decade, from 8·3 million (3·3 million–17·2 million) apparent cases in 1990, to 58·4 million (23·6 million–121·9 million) apparent cases in 2013. When accounting for disability from moderate and severe acute dengue, and post-dengue chronic fatigue, 566 000 (186 000–1 415 000) years lived with disability were attributable to dengue in 2013. Considering fatal and non-fatal outcomes together, dengue was responsible for 1·14 million (0·73 million–1·98 million) disability-adjusted life-years in 2013…..the true symptomatic incidence of dengue probably falls within the commonly cited range of 50 million to 100 million cases per year. ”
** Many of the fatal dengue cases in 2013 occurred in Southeast Asia (5,376 deaths) and South Asia (2,132 deaths).
** Death rates in tropical and central Latin America and the Caribbean increased from 1990 to 2013
** Most dengue-related deaths (7,018) in 2013 occurred in individuals belonging to the lower middle-class income group.
** The researchers acknowledge that their models resulted in estimates of mortality incidence that are significantly lower than the World Health Organization’s estimate of 10,000 to 20,000 deaths caused by dengue each year.
