Global & Disaster Medicine

Clarithromycin and naproxen were dosed at 500 mg twice daily and 200 mg twice daily, respectively, along with oseltamivir and amoxicillin-clavulanate: The combination group achieved lower 30-day and 90-day mortality as well as shorter lengths of stay than the controls.

Hung IFN, To KKW, Chan JFW, et al. Efficacy of clarithromycin-naproxen-oseltamivir combination in the treatment of patients hospitalized for influenza A(H3N2) infection. Chest 2017;151:1069-1080.

“….Though limited by its single center, open-label status, this study nonetheless provides important proof-of-concept that antiviral therapy for hospitalized influenza patients can be supplemented with clarithromycin and naproxen to achieve better clinical outcomes…..”


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